Making decisions about knee replacement as an older person with multiple conditions

Steroid injections

Steroid injections, also called corticosteroid injections, can be used to treat knee pain and swelling, and are given by a healthcare professional. Doctors usually recommend people have no more than four steroid injections in 12 months and to have them three months apart. They can take a few days to start working and wear off after a few weeks or months, although for some the pain relief lasts a lot longer.

Some of the people we talked to had had steroid injections in their knee. This section covers the changing impact of steroid injections across time.

A physiotherapist explains about steroid injections for knee osteoarthritis.

A physiotherapist explains about steroid injections for knee osteoarthritis.

SHOW TEXT VERSION
PRINT TRANSCRIPT

So, the way I look at steroid injections depends on the stage of the osteoarthritis really. So, as I think I mentioned earlier on, in the early stages of osteoarthritis where the joint is not too damaged, if you like, degenerated - it's the sleeve around the joint that's largely responsible for the pain. It's called the joint capsule. So, for patients with early osteoarthritis, it makes sense to me that if you inject steroid, corticosteroid, local anaesthetic into that joint, bathe the capsule in medicine, they're much more likely to have a good outcome because you're- it's the capsule that's causing the pain.

As the osteoarthritis advances, the capsule is still inflamed, that's for sure, but it becomes more about bone-on-bone pain. Which patients often describe as different. Now if you put steroid into a severely arthritic joint, you're likely to get temporary relief because while you’ll bathe the capsule and settle the capsule down, you're not going to do anything about that bone-on-bone pain. Certainly nothing prolonged, so the pain will come back. And what we tend to see – there’s not a lot written about this but some clinicians have noticed that when you give a patient with severe osteoarthritis a steroid injection, when the pain wears off, sometimes it appears to be worse than it was before. We don't really know why that is but it's called rebound pain. So therefore, steroid injections are generally limited for people with severe arthritis unless surgery is not an option for health reasons or the patient doesn't want an operation. In that situation, yes, it's worth a try. But we just need to make sure that the patient's expectations are aligned with ours.

Changing impacts of steroid injections

People we talked to experienced mixed success with steroid injections. Some people had been having steroid injections for other health conditions over many years. Toby had steroid injections on a regular basis in his knees and shoulders for rheumatoid arthritis. Marjorie had not had steroid injections on her knees but she was aware of them and what they could do from previously having them for ligament problems.

For people who had steroid injections for knee pain, some found they were effective in taking away pain for several months, others for just a few days or weeks, and some said having a steroid injection did not make any difference.

A steroid injection helped to manage Tina’s pain effectively while waiting for a glaucoma operation.

A steroid injection helped to manage Tina’s pain effectively while waiting for a glaucoma operation.

Age at interview: 76
Sex: Female
SHOW TEXT VERSION
PRINT TRANSCRIPT

It’s so unpredictable. In the morning, before the walk, I was taking painkillers before I went all the time. But I did recently have the injection, the steroid injection.

It hasn’t been quite as pain relieving as when I had it about two years or so ago. But it has made a considerable difference, though I haven’t had to take-, I only take paracetamol. I have been prescribed something stronger, but I delayed it because of the glaucoma operation because there are side effects, as there are with most tablets.

And one of them was to do with eyes. So, I thought well, I’d be a bit stupid to start something that gave problems with your eyes when I was just about to have [laugh] an eye operation.

So, I left it and, so far, haven’t had to resort to the stronger ones. And at the moment, I’m only taking the paracetamol in the morning before we go because okay, it’s not very long since I had the injection but you can tell it’s sort of beginning to wear off, it doesn’t actually last all that long.

Steroid injections had been an effective way to manage Bridget’s knee pain.

Steroid injections had been an effective way to manage Bridget’s knee pain.

Age at interview: 86
Sex: Female
SHOW TEXT VERSION
PRINT TRANSCRIPT

I’ve always had knee problems for some reason, but, oh, quite a few years ago, probably about the same time my GP gave me cortisone injections and they worked really well for about- I only had one lot and they worked for about four years and then I had them again - and then I’ve actually forgotten the timeline - I think I had two lots with him.

And then last summer I was going on holiday and my knees had got quite sore, so he did them again - but he said he couldn't do any more. I don’t know whether that’s the National Health or what, I didn’t even ask.

So because they’d worked so well before, I didn’t think it would be anything urgent and they worked straightaway. But then by November my knees had got incredibly painful, so to the point where I could hardly walk.

I knew he wouldn't do any more injections, so I- a friend of mine had known a [knee specialist/surgeon] and recommended him, so I went to see him privately and he injected one knee, my left knee, and said that he could inject them every three or four months. But he thought with modern, more recent technology, they could probably operate on them, so he referred me back to my GP for treatment under the National Health.

So that was where we were at, and then they got painful again recently - about three weeks ago - and I decided I would just go back to him, and I went back to him and he injected both knees this time, and touchwood, so far, they’ve been fine.

Oh good.

But I do now have an appointment at the orthopaedic hospital under National Health.

Petra has had many successful steroid injections over the years. She said having them “tides you over a little bit until you come up on the waiting list.” Michael X had steroid injection in his knee three or four times over several years. He found they usually wore off after 4 to 6 weeks.

However, some people felt that steroid injections had become less effective in reducing pain for them. Dorothy had steroid injections in the past which had sometimes alleviated the pain. But they were no longer an option as an X-ray showed her knee joint has deteriorated and is “bone on bone”, which meant that the knee cartilage was very worn down. Janet described her first steroid injections as “fairly miraculous” but the effect of the second didn’t last as long. Pete’s first steroid injection lasted three to four months while his second one only lasted a week or two.

Previously steroid injections worked for Ged but more recently he had three injections which “haven’t done anything at all” and his knee had worsened.

Previously steroid injections worked for Ged but more recently he had three injections which “haven’t done anything at all” and his knee had worsened.

Age at interview: 81
Sex: Male
SHOW TEXT VERSION
PRINT TRANSCRIPT

Yes, I had one in in that knee years ago when I was, lived in [town]. And I went in there and had the injection, came out and I thought ‘this is good. I can’t feel a thing’, you know. It was absolutely fine. It was brilliant. On this occasion now, with my right knee, the first one the doctor gave me it didn’t do anything, it didn’t do anything at all. I think I’ve had; I think I’ve had three altogether. And no, they haven’t done anything at all. Steroid injections in my leg. But it did initially, years back because I suppose years ago, my knee wasn’t in such a bad state that it is now. And the steroid injection helped. As your knee gets worse, it degenerates and what have you, so on and so forth, steroid injections don’t work.

Victoria had three steroid injections over 18 months before her knee replacement surgery. The first two worked but the last didn’t and she was referred to an orthopaedic surgeon.

Victoria had three steroid injections over 18 months before her knee replacement surgery. The first two worked but the last didn’t and she was referred to an orthopaedic surgeon.

Age at interview: 78
Sex: Female
SHOW TEXT VERSION
PRINT TRANSCRIPT

Well, I had it four years ago when I had my other knee done. And, years ago, you used to be able to get it, you could get one every six months.

So, I had one in six months and it definitely helped and I had one another six months and it helped. And then the next time I had it, it didn't work, so when they done the X-ray, they seen there was no cartridge left for it to go into.

So, when the doctor said, they send me for this, I was hoping it would work, but it didn't.

As I say, then when they X-rayed it, they said, “There’s no cartridge there to put, you know.” So that’s when they said they’ll refer me to the hospital.

Others told us that the effects of their steroid injection only lasted for a short time. Derek has had one steroid injection in his knee which was “marvellous” but the pain relief only lasted “a wonderful 5 days.”

For some people, including Ruth, Clive, Victoria and Stuart, steroid injections had no effect on their knee pain. Stuart thought this was because his main problem was pain coming from the ligaments down the leg rather than his knee joint. Ged was unable to have a steroid injection because he had been advised that if he had it too close to when his knee operation might be, then they wouldn’t be able to do the operation, as there could be an increased risk of postoperative infection.

Copyright © 2024 University of Oxford. All rights reserved.